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What To Expect

What to Expect During Your Colonoscopy

  • During a colonoscopy, your doctor will very carefully put a thin, flexible tube with a lighted fiber optic camera, called a colonoscope, into your rectum and colon. The colonoscope sends pictures of the inside of your colon to a video screen so your doctor can check for polyps (abnormal growths) or colon cancer. If your doctor does see a polyp, it can be removed during your colonoscopy.

  • You will have an IV placed in a vein in your hand or arm so you can be given medicines and fluids. Right before the test begins, your doctor will give you a mild sedative to help make you as comfortable as possible. As you lie on your side, your doctor will slowly and gently put the colonoscope into your rectum and up through your colon. You may feel some pressure, bloating, or cramping during the test.

  • After your test, you will have to rest for a while until the effects of the medicine wear off. While you are resting, your doctor will talk to you about the results of your test and whether any polyps were removed. If a biopsy was performed you can expect to get the results in a few days.

  • Do not drive yourself home after your test. Ask a loved one or friend to go with you on the day of your exam.

What to Expect with SUPREP®BOWEL PREP KIT

Be sure to follow your doctor’s instructions and carefully read the information that comes with SUPREP Bowel Prep Kit. Your doctor will tell you when it is time to begin taking SUPREP Bowel Prep Kit.

SUPREP Bowel Prep Kit is a low-volume bowel preparation that is taken as a split-dose regimen. A split-dose regimen means that you take two 6-ounce bottles of SUPREP Bowel Prep Kit. The first 6-ounce bottle is taken the evening before your colonoscopy and the second 6-ounce bottle is taken the morning of your colonoscopy.

After taking your first medicinal dose, you must drink two (2) more 16-ounce containers of water over the next hour. Upon taking the second medicinal dose, it is important to again drink two (2) 16-ounce containers of water over the next hour.

In clinical studies, the most common side effects that people experienced with SUPREP Bowel Prep Kit were overall discomfort, abdominal distention, abdominal pain, nausea, vomiting and headache. Call your doctor if you have any questions about taking SUPREP Bowel Prep Kit.


SUPREP® Bowel Prep Kit (sodium sulfate, potassium sulfate and magnesium sulfate) Oral Solution is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients 12 years of age and older.


Use is contraindicated in the following conditions: gastrointestinal (GI) obstruction or ileus, bowel perforation, toxic colitis or toxic megacolon, gastric retention, hypersensitivity to any ingredients in SUPREP Bowel Prep Kit.


Each bottle must be diluted with water to a final volume of 16 ounces (Adults) and 12 ounces (Pediatric patients 12 years of age and older). Must consume additional water after each dose. Stop consumption of all fluids at least 2 hours prior to the colonoscopy.


Risk of fluid and electrolyte abnormalities: Encourage adequate hydration, assess concurrent medications, and consider laboratory assessments prior to and after each use; Cardiac arrhythmias: Consider pre-dose and post-colonoscopy ECGs in patients at increased risk; Seizures: Use caution in patients with a history of seizures and patients at increased risk of seizures, including medications that lower the seizure threshold; Patients with renal impairment or taking medications that affect renal functions: Use caution, ensure adequate hydration and consider laboratory testing; Suspected GI obstruction or perforation: Rule out the diagnosis before administration; Patients at risk for aspiration: Observe during administration.


Most common adverse reactions: Adults: (> 2%) are overall discomfort, abdominal distention, abdominal pain, nausea, and vomiting; Pediatric Patients (>10%) are nausea, abdominal pain, abdominal bloating and vomiting.


Drugs that may increase the risk of fluid and electrolyte abnormalities.

View the Full Prescribing Information and Medication Guide.

References: 1. IQVIA. National Prescription Audit Report. November 2021. 2. SUPREP Bowel Prep Kit [package insert]. Braintree, MA: Braintree Laboratories, Inc. 3. American Society of Anesthesiologists Committee on Standards and Practice Parameters. Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures. Anesthesiology. 2011;114(3):495-511.